/medicare/b/weblog/posts/balancing-opioid-use-and-abuseOpioids are helpful when taken the right way. When misused, they can lead to dependence. This can lead to overdose or even accidental death. In 2023, about 76% of all overdose deaths involved opioids. Opioid misuse and related deaths have been consi.en-USTelligent Community 12